Faculty of Biology, University of Latvia
Hard copy: ISSN 1691–8088
On-line: ISSN 2255–9582
Acta Univ Latv (2003) 662: 67–79
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Acta Univ Latv (2003) 662: 67–79

Orginal Article

A new approach to study the origin of genes and introns

Nora Ievina*, Gunars Chipens
Department of Peptide chemistry, Latvian Institute of Organic Synthesis, Aizkraukles iela 21, Rīga, LV-1006, Latvia
*Corresponding author, E-mail: ievina@osi.lv


Eukariotic genomes have two main structural components – different types of repetitive nucleic acids and unique, at fi rst glance nonrepetitive sequences of gene coding parts. A new methodology of sequence analysis based on the structure of the second genetic code can be used to reveal molecular relics in protein and gene structures of tubulins and small G proteins. These are sequences formed of repeat units having identical regularity, as well as ancestral immobile introns distributed in the exon row with the same regularity. A new theory is advanced explaining exon and intron origin from common precursors – highly repetitive simple structure nucleic acids – during the early periods of evolution.

Key words: Multiplication of nucleotides, old ancestral introns, origin of introns, repeat units of genes and proteins, small G proteins, tubulins.

Acta Univ Latv (2003) 662: 67–79
 DOI: http://doi.org/10.22364/eeb

Prof. Gederts Ievinsh
Published by
University of Latvia

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