Faculty of Biology, University of Latvia
EEB
Hard copy: ISSN 1691–8088
On-line: ISSN 2255–9582
Env Exp Biol (2013) 11: 81–89
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Environmental and
Experimental
Biology

Env Exp Biol (2013) 11: 81–89

Original Article

Serum biochemical responses under stress of cypermethrin in albino rat

Brijender Bhushan*, Sunita Pande, Nishi Saxena, Prabhu Narain Saxena
Toxicology Laboratory, Department of Zoology, School of Life Sciences, Dr. B.R. Ambedkar University, Khandari Campus, Agra 282002, India
*Corresponding author, E-mail: bantu.sls@gmail.com

Abstract

Toxicity due to acute (1 day) and subchronic (7, 14, 21 and 28 days) orally administrated doses of cypermethrin in albino rats was evaluated using serum biochemical parameters (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, total lipids, phospholipids, glycerides, total proteins, cholesterol and bilirubin). The parameters had significantly higher values in treated rats with cypermethrin-associated toxicity. One more set was run simultaneously for 22 more days following 28 days of subchronic cypermethrin intoxication to evaluate possible recovery. In the recovery period, most of the values reached normal level pointing towards degradation of cypermethrin in the treated animals.

Key words: albino rats, blood biochemistry, cypermethrin, pyrethroid toxicity.

 
Env Exp Biol (2013) 11: 81–89
 DOI: http://doi.org/10.22364/eeb
EEB

Editor-in-Chief
Prof. Gederts Ievinsh



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University of Latvia

 
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