Faculty of Biology, University of Latvia | ||||||
Hard copy: ISSN 1691–8088
On-line: ISSN 2255–9582 |
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Environmental and Experimental Biology |
Environmental and Experimental Biology is an international print/electronic journal published four times a year, owned by a non-profit-making government-funded university. Original research papers covering all aspects of modern biology are welcome. The EEB publishes original articles, brief communications and reviews. Founded in 2003 as Acta Universitatis Latviensis ser. Biology, since 2010 EEB.
Publication is free of charge.
Nazir S., Yasien U., Ashraf A., Ganie S.A., Bhat A.W.
2024. Unravelling the role of Set2 protein domains in H3K36 methylation in Saccharomyces cerevisiae.
Environmental and Experimental Biology 22: 87–93.
DOI: 10.22364/eeb.22.09
Comparison of the protein domains of budding yeast Set2 and human SETD2. The architectural organization of Set2 in budding yeast and its human homolog SETD2 exhibits remarkable conservation of domains: Both proteins feature a highly conserved domain arrangement, including a catalytic SET domain responsible for methyltransferase activity. Adjacent to the SET domain lies the Autoinhibitory Domain (AID), whose precise function remains largely elusive. Following the AID, a tandem arrangement of the WW, coiled-coil (CC) domains, and Set2-Rpb1 Interaction (SRI) domain are located at the C-terminal end.