Faculty of Biology, University of Latvia
Hard copy: ISSN 1691–8088
On-line: ISSN 2255–9582
Env Exp Biol (2010) 8: 107–110
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Environmental and

Env Exp Biol (2010) 8: 107–110

Brief Communication

Method to test influence of bio-implants on blood cells by consecutive measurements

Alevtina Leice1*, Yuri Dekhtyar2, Natalya Britzina3
1Latvian University P. Stradins Medical College, Bruninieku 28, Riga LV-1011, Latvia
2Riga Technical University, Ezermalas 6, Riga LV-1006, Latvia
3Latvian University Institute of Cardiology, Pilsonu 13, Riga LV-1002, Latvia
*Corresponding author, E-mail: alevtina.leice@inbox.lv


The study was directed to the development of a method for evaluation of the changes in 15 blood parameters of venous blood specimens under the contact with biomaterials. Plain titanium plates and also titanium deposited with a hydroxyapatite ceramic layer were chosen for testing. Titanium free blood specimens were used as a reference. Five consecutive tests of experimental and reference blood samples were performed simultaneously. One way analysis of variance was used to determine significant difference of the blood parameters from baseline values. The results demonstrated the method as sensitive to reveal changes in erythrocytes, subpopulations of white blood cells and platelets measured by an ABX Micros OT automated hematology analyzer.

Key words: bio-implant, blood cells, blood contact in vitro method.

Env Exp Biol (2010) 8: 107–110
 DOI: http://doi.org/10.22364/eeb

Prof. Gederts Ievinsh
Published by
University of Latvia

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