Env Exp Biol (2010) 8: 107

Brief Communication

Method to test influence of bio-implants on blood cells by consecutive measurements

Alevtina Leice^1*, Yuri Dekhtyar², Natalya Britzina³

¹Latvian University P. Stradins Medical College, Bruninieku 28, Riga LV-1011, Latvia
²Riga Technical University, Ezermalas 6, Riga LV-1006, Latvia
³Latvian University Institute of Cardiology, Pilsonu 13, Riga LV-1002, Latvia
^*Corresponding author, E-mail: alevtina.leice@inbox.lv

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Abstract

The study was directed to the development of a method for evaluation of the changes in 15 blood parameters of venous blood specimens under the contact with biomaterials. Plain titanium plates and also titanium deposited with a hydroxyapatite ceramic layer were chosen for testing. Titanium free blood specimens were used as a reference. Five consecutive tests of experimental and reference blood samples were performed simultaneously. One way analysis of variance was used to determine significant difference of the blood parameters from baseline values. The results demonstrated the method as sensitive to reveal changes in erythrocytes, subpopulations of white blood cells and platelets measured by an ABX Micros OT automated hematology analyzer.

Key words: bio-implant, blood cells, blood contact in vitro method.

Env Exp Biol (2010) 8: 107–110

DOI: http://doi.org/10.22364/eeb

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Faculty of Biology, University of Latvia
				Hard copy: ISSN 1691–8088 On-line: ISSN 2255–9582 Env Exp Biol (2010) 8: 107–110 DOI: https://doi.org/10.22364/eeb
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