Env Exp Biol (2012) 10: 107–112

Systemic pro-inflammatory molecule response to acute submaximal exercise in moderately and highly trained athletes

Abstract

The effect of training status on acute exercise-induced release of pro-inflammatory biomarkers in circulatory system was studied in 10 moderately trained and seven highly trained athletes. The subjects performed an hour of submaximal bicycle exercise at workload equal to ~70% of heart rate reserve. Venous blood samples were collected 15 min before and immediately after the exercise. Intereukin-6, tumor necrosis factor-α, and monocyte chemotactic protein-1 response to exercise was similar in moderately trained and highly trained athletes (2.5 ± 2.4 vs. 1.0 ± 1.0 pg mL^–1; 0.4 ± 0.6 vs. 0.8 ± 0.8 pg mL^–1; 50 ± 67 vs. 74 ± 116 pg mL^–1, respectively), suggesting that training status had no impact on cytokine and monocyte chemotactic protein-1 post-exercise concentrations with this experimental model.