Env Exp Biol (2013) 11: 81–89

Serum biochemical responses under stress of cypermethrin in albino rat

Abstract

Toxicity due to acute (1 day) and subchronic (7, 14, 21 and 28 days) orally administrated doses of cypermethrin in albino rats was evaluated using serum biochemical parameters (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, total lipids, phospholipids, glycerides, total proteins, cholesterol and bilirubin). The parameters had significantly higher values in treated rats with cypermethrin-associated toxicity. One more set was run simultaneously for 22 more days following 28 days of subchronic cypermethrin intoxication to evaluate possible recovery. In the recovery period, most of the values reached normal level pointing towards degradation of cypermethrin in the treated animals.